Membrane Proteins: Structure and Function


This course will discuss the structure and function of membrane proteins with an emphasis on relevant methodologies. Selected transporters, channels,  pumps and G-protein-coupled-receptors (GPCRs) will be used as examples to illustrate the current state of the art of membrane protein biochemistry.  Molecular aspects of disease processes linked to membrane proteins will be discussed, with an emphasis on how 3D structural information provides a basis for understanding function.

General principles of membrane protein structure will be discussed.

Course Next Offered

September 2019

Course Time and Location

Fall Term (Sept. - Dec.)
Tuesday, Thursday 11am - 12 noon
Room 4279 Medical Sciences Building



Enrollment Limit

Yes — 80

Method of Student Evaluation

2 Assignments (total 30%)
3 Quizzes (10%)
1 Midterm (30%)
Final exam (40%)

Recommended Reading

We will be discussing current state of the art, and readings will be assigned from the current scientific literature.

Lecture notes will be provided in class and/or through Quercus.

Membrane Structural Biology 2nd Edition by Mary Luckey, Cambridge University Press (2014). (not required).


Oliver P. Ernst

Oliver P. Ernst

MSB, Room 5316A
1 King's College Circle


Last Updated 9 August 2019