Proteins: From Structure to Proteomics



Proteins are the main functional units of the cell. In this course, a detailed overview of protein structure and function will be given with strong emphasis on the basic principles in the field. Students will be introduced to folded and intrinsically disordered proteins. Biophysical methods to study protein stability and folding will be discussed, as well as experimental approaches to determine protein structure and function. Students will be introduced to catalysis, kinetics, and the mechanisms that regulate enzyme activity. Finally, proteomic methods to studying protein networks in cells will be presented. The course will offer a solid basis in protein biochemistry. It is recommended for those interested in pursuing graduate studies or professional degrees in health or medicine.



Students will learn fundamental principles about protein structure and function, as well as techniques that are used to study proteins in vitro and in cells. By integrating these concepts, students will conceptualize proteins as dynamic, three-dimensional molecules that specifically bind ligands to execute one or more critical roles in the cell. Students will apply this knowledge to critically analyze and discuss scientific literature, answer problem-based questions, and explain why abnormal protein structure and function can disrupt cellular homeostasis.

Course Next Offered

January 2021

Course Time and Location

The course will be held every Monday, Wednesday, and Friday from 1:00 pm – 2:00 pm online.


BCH210H1/BCH242Y1 are mandatory. In addition, this course assumes you have a basic understanding of biology, chemistry, physics, and math.

Enrollment Limit

Yes — 80


Haley Wyatt

Haley Wyatt

MaRS Center, West Tower, Room 1521A
661 University Avenue


Last Updated 3 November 2020