Regulation of Signalling Pathways

BCH426H (BCH1426H)

A variety of subjects relating to signal transduction are investigated. Topics include how extracellular signals such as morphogens, growth factors or insulin, receive and transmit messages to intracellular proteins including kinases and phosphatases to control cellular proliferation and differentiation. High-throughput genomic and proteomic approaches to study signalling pathways are also explored.

Topics to be covered

  • Liliana Attisano: General signal transduction, TGFβ signalling and pathway cross-talk
  • Igor Stagljar: Proteomic and Genomic approaches
  • Amira Klip: Pathways that regulate glucose transporters and their metabolic implications
  • Daniela Rotin: Ubiquitination pathways

Course Next Offered

Fall 2023

Course Time and Location

Room: MSB2173
1:00 - 2:00, Mondays and Wednesdays

Prerequisites

BCH210H1 / BCH242Y1;
BCH311H1 / MGY311Y1 / PSL350H1

Distribution Requirement Status: This is a Science course
Breadth Requirement: Living Things and Their Environment (4)

Enrollment Limit

Yes — 80

Method of Student Evaluation

Two Midterm tests (50-60%*) and a final exam (40-50%*). *varies from year to year

Coordinator

Liliana Attisano

Liliana Attisano

160 College Street, room 1008
416-946-3129
liliana.attisano@utoronto.ca

Instructors

Last Updated 17 October 2023