Regulation of Signalling Pathways
BCH426H (BCH1426H)
A variety of subjects relating to signal transduction are investigated. Topics include how extracellular signals such as morphogens, growth factors or insulin, receive and transmit messages to intracellular proteins including kinases and phosphatases to control cellular proliferation and differentiation. High-throughput genomic and proteomic approaches to study signalling pathways are also explored.
Topics to be covered
- Liliana Attisano: General signal transduction, TGFβ signalling and pathway cross-talk
- Igor Stagljar: Proteomic and Genomic approaches
- Amira Klip: Pathways that regulate glucose transporters and their metabolic implications
- Daniela Rotin: Ubiquitination pathways
Course Next Offered
Fall 2023
Course Time and Location
Room: MSB2173
1:00 - 2:00, Mondays and Wednesdays
Prerequisites
BCH210H1 / BCH242Y1;
BCH311H1 / MGY311Y1 / PSL350H1
Distribution Requirement Status: This is a Science course
Breadth Requirement: Living Things and Their Environment (4)
Enrollment Limit
Yes — 80
Method of Student Evaluation
Two Midterm tests (50-60%*) and a final exam (40-50%*). *varies from year to year