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Professor

Liliana Attisano

Intracellular signalling, neuronal morphology, developmental processes, high throughput robotics, cancer

PhD

Location
Donnelly Centre for Cellular and Biomolecular Research
Address
160 College St., Rm. 1008, Toronto, Ontario Canada M5S 3E1
Research Areas
Cell Biology, Molecular Medicine and Drug Discovery, Regulation of Gene Expression, Signal Transduction
Role
Faculty
Accepting
Graduate Student Rotations - Current Term - Please Enquire, Undergraduate Research - Summer - Please Enquire, Undergraduate Research - Fall and Winter - Please Enquire

Dr. Attisano completed her PhD at the University of Toronto and conducted post-doctoral research at Memorial Sloan-Kettering Cancer Center in NYC, NY. She currently holds a Canada Research Chair in Signalling Networks in Cancer.

My laboratory focuses on understanding how intracellular signalling cascades receive and then transmit extracellular signals and thereby modulate complex biological responses. Current areas of particular interest are the TGFbeta, Wnt and Hippo signalling pathways, whose disruption is associated with numerous human cancers. My lab also studies pathways that regulate neuronal morphology, including the formation of axons and dendrites in primary neurons. We use mammalian cell cultures, mice and most recently human stem cell-derived organoid models to better understand how disruptions in signalling pathways underlie human disease processes including cancer and neurological disorders.  Dr. Attisano established the Applied Organoid Core Facility located in the Donnelly Centre, whose mission is to produce and provide organoids to users as well as holding workshops and providing one-on-one training in stem cell culturing and organoid generation. 

 

Courses Taught

BCH2132H Modelling Human Diseases from Cells to Organoids
BCH374Y1 Research Project in Biochemistry
BCH473Y Advanced Research Project in Biochemistry