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Research Areas

Research in the Department of Biochemistry at the University of Toronto spans a wide and dynamic range of topics at the forefront of molecular life sciences. Our investigators explore the fundamental principles that govern cellular function, molecular structure, and genetic regulation, while also advancing new methods in computation, pedagogy, and drug discovery. The following research areas reflect the depth and diversity of inquiry pursued in our department, where faculty and trainees work collaboratively to uncover the molecular mechanisms of life and translate their discoveries into real-world impact.

Cell Biology is the study of the structure and function of cells, fundamental units of life that become organized into tissues and organisms.

Biochemical research programs are becoming increasingly reliant on adopting computer-based approaches for the integration and visualization of so-called 'big data'.

Developing effective science pedagogy is essential to enhancing the student experience, promoting critical thinking, and training our future scientists.

The maintenance of genome integrity is critical for normal gene expression, cell division, tissue homeostasis, and healthy organism survival.

Biological membranes are complex and dynamic ensembles of lipids and proteins, which define the limits of cells and organelles and carry out a variety of specialized functions.

The study of prokaryotes and phage has implications for human disease, drug discovery, and the development of new technologies.

Biochemistry is the central discipline in the discovery of new medicines.

The three-dimensional structures of biological molecules, their interactions and molecular motion provide the fundamental basis for understanding how they mediate their functions.

The proper functioning of a cell and its ultimate developmental fate is determined by specific patterns of gene expression.

Signal transduction pathways regulate diverse processes in cell division, development, and differentiation.