Alexander Ensminger
PhD
The Ensminger lab is interested in the evolution of microbial pathogens and the mechanisms by which these diminutive organisms persist in our environment and make us sick.
We focus our attention primarily on Legionella pneumophila, a remarkable bacterial pathogen that maintains the microbial world’s largest known arsenal of translocated effectors (with over 300 identified to date). Unlocking the secrets of this arsenal holds immense promise to provide novel insight into fundamental eukaryotic pathways, human health, and disease.
We use a variety of approaches in the lab, from advanced sequencing technologies (Illumina, Pacific Biosciences), bioinformatics, microbial genetics, high-throughput genetic and chemogenetic screening, and experimental evolution.
Appointments, Cross Affiliations, Memberships
Associate Graduate Coordinator - Department of Biochemistry
Associate Professor - Department of Molecular Genetics
Courses Taught
BCH428H Genomics of microbial communities in human health and beyond
BCH473Y Advanced Research Project in Biochemistry