Jean-Philippe Julien
PhD
Dr. Julien’s laboratory characterizes the mode of action of antibodies at the molecular level to guide the design of next-generation vaccines and therapies. A major focus of his laboratory is to use integrative structural biology approaches and biophysical techniques to characterize antibody-antigen interactions. This knowledge is then applied to develop next-generation therapeutic molecules fit-for-purpose using protein engineering. Through this work, Dr. Julien’s laboratory is generating three-dimensional glimpses of antibody mechanisms of action, with already several examples of how this information can be translated into the development of vaccine candidates against malaria and HIV-1, and antibodies with improved biological and developability
Appointments, Cross Affiliations, Memberships
Senior Scientist, Hospital for Sick Children
Associate Professor, Department of Immunology
Canada Research Chair in Structural Immunology,
CIFAR Azrieli Global Scholar
Member of the College of the Royal Society of Canada
Courses Taught
BCH2109H Current Topics in Therapeutic Antibodies
BCH473Y Advanced Research Project in Biochemistry
BCH425H Structural Biology: Principles and Practice
IMM428 Molecular Immunology
Awards
2022 — Canada Research Chair in Structural Immunology
2021 — Canadian Society for Molecular Biosciences New Investigator Award
2020 — Canadian Society for Immunology New Investigator Award
2020 — Amgen Young Investigator Award
2020 — International Union of Crystallography W. H. and W. L. Bragg Prize
2019 — Member of the College of New Scholars, Artists and Scientists of the Royal Society of Canada
2019 — CIFAR Azrieli Global Scholar
2019 — Ontario Ministry of Research, Innovation and Science Early Researcher Award