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Associate Professor

Andrew Wilde

cytokinesis, tumorigenesis, genome stability, oogenesis

PhD

Location
MaRS Discovery Centre - West Tower Floor 15/16
Address
661 University Ave., Rm. 1516, Toronto, Ontario Canada M5G 1M1
Research Areas
Cell Biology, Genome Organization and Integrity, Membranes and Transport Mechanisms, Signal Transduction
Role
Faculty
Accepting
Graduate Student Rotations - Current Term - Please Enquire, Undergraduate Research - Summer - Please Enquire, Undergraduate Research - Fall and Winter - Please Enquire

Andrew Wilde hails from the UK and moved to North America for Post-Doctoral work with Frances Brodsky at UCSF where he discovered novel links between receptor tyrosine kinase signaling and endocytosis. Subsequently, he moved to the Carnegie Institution in Baltimore to work with Yixian Zheng where he discovered a chromosome based signaling pathway that spatially organizes a mitotic cell. Andrew moved to Toronto in 2001 where he held a Canada Research Chair in Cell Biology. Andrew has continued his work examining how signals spatially co-ordinate mitosis with a particular focus on the co-ordination of chromosome segregation with membrane re-organization during cytokinesis and the role of tumor suppressors in regulating this process to ensure genome stability.

Cell Division in Tumor Formation and Oogenesis

Our research focus is to understand how cells divide. In particular we focus on the role of cell division in tumor formation and oogenesis. We take a multi-faceted approach combining biochemistry and live imaging to analyze cell division in frog eggs, Drosophila embryos and mammalian cells.

 

Appointments, Cross Affiliations, Memberships

Associate Professor, Department of Molecular Genetics, University of Toronto

Courses Taught

BCH 2134H Cytoskeletal Dynamics
BCH479H1 Advanced Seminar in Biochemistry
BCH473Y Advanced Research Project in Biochemistry
BCH448H Structure and Function of the Nucleus
MGY311Y1 Molecular Biology
MMG1012H Cell Polarity

Awards and Distinctions

2002-2012 — Canada Research Chair  
2001 — Premier's Research Excellence Award