Membrane Proteins: Structure and Function - BCH422H1
This course will discuss the structure and function of membrane proteins with an emphasis on relevant methodologies. Selected transporters, channels, pumps and G-protein-coupled-receptors (GPCRs) will be used as examples to illustrate the current state of the art of membrane protein biochemistry. Molecular aspects of disease processes linked to membrane proteins will be discussed, with an emphasis on how 3D structural information provides a basis for understanding function.
We will be discussing current state of the art, and readings will be assigned from the current scientific literature. Lecture notes will be provided in class and/or through Quercus.
Prerequisites:
BCH210H1/242Y,
BCH311H1/MGY311Y/PSL350H1
Course Coordinator:
Oliver Ernst
Course Instructors:
Oliver Ernst, Gil Privé, Régis Pomès
Scheduling:
Fall Term (Sept. - Dec.)
Tuesdays and Thursdays: 11am - 12 noon
Enrollment Cap:
65
Recommended Reading:
Membrane Structural Biology 2nd Edition by Mary Luckey, Cambridge University Press (2014). (not required).