Wyatt

An open-source platform to quantify subnuclear foci and protein colocalization in response to replication stress

7 July 2021|

Nuclear reorganization, including the localization of proteins into discrete subnuclear foci, is a hallmark of the cellular response to DNA damage and replication stress. These foci are thought to represent transient environments or repair factories, in which the lesion is sequestered with molecules and co-factors that catalyze repair. For example, nuclear foci contain signaling proteins that recruit transducer proteins. One important class of transducers is the structure-selective endonucleases, such as […]

Biochemistry Specialists, Class of 2021

3 June 2021|

Congratulations to our graduating Biochemistry Specialists! We are very proud of the accomplishments of this impressive group of young scientists. With an ongoing thirst for knowledge and discovery, all ten are bound for exciting graduate programs in Biochemistry, Chemistry, Biomedical Communications, and Plant and Microbial Biology, at the University of Toronto, McGill University, and UC Berkeley. Best of luck in grad school!