6 June 2016|

In a paper recently published in Nature Chemical Biology, Simon Wisnovsky in Kelley laboratory describes a high-throughput screening study that leverages small-molecule probes to look for new DNA repair and replication factors in human mitochondria.  The study uncovered a DNA polymerase that is essential for mitochondrial function that had never been observed in the organelle before.  Given the importance of mitochondria as cellular energy generators and trigger points […]