sick kids

An image of the cover of JBC.

Breaking down the protective armour of the mold Aspergillus fumigatus

3 December 2015|

Collaboration between Dr. P. Lynne Howell  and Dr. Don Sheppard has led to the discovery of a novel class of enzymes and an increased understanding of how to potentially fight a common and deadly fungal infection.

Read more about this publication here:

Listen to the CBC Radio interview with Dr. Don Sheppard.

PLVAP Diagram

Aleixo Muise and Sick Kids researchers find defect in blood vessels the cause of new intestinal disease

6 August 2015|

In a study published in Cellular and Molecular Gastroenterology and Hepatology, Aleixo Muise, Clinician-Scientist and Co-Director of the IBD Centre, and a team of Sick Kids researchers reveal that a genetic defect causes a mutation of the PLVAP gene. The mutation leads to the loss of the protein filter in blood vessels in the bowel. Further research into this new disease may lead to new treatments and a […]