DNA Replication Stress Causes Mutations
Grant Brown’s lab at the Donnelly Centre has characterized a new mutagenic ssDNA gap filling pathway in budding yeast. Their findings will be published in the March 7th issue of Molecular Cell.
DNA replication is a fundamental process that occurs before every cell division and must be completed in a timely and accurate fashion. Under normal cellular conditions this reaction is carried out by the highly processive and accurate replicative […]
