Dr. Karen Maxwell

A chemical defence for bacteria against phage infection

20 December 2018|

Just published in Nature (2018) 564:283-286, the Maxwell lab, in collaboration with the Nodwell lab, report the discovery of a chemical anti-phage defence system that is widespread in the bacterial family of Streptomyces. These produce three molecules that insert into DNA which block phage replication. This mechanism of anti-phage defence probably has a major evolutionary role in shaping bacterial communities.

Davidson and Maxwell help discover off-switches for CRISPR

31 January 2017|

 

Featured on the cover of Cell, Biochemistry’s Dr. Alan Davidson and Dr. Karen Maxwell helped to discover how to turn off CRISPR. Read the full story.