Bear

Bear Lab shows that a new Cystic Fibrosis treatment improves function from a rare CFTR mutation in patient tissue

14 July 2017|

The laboratory of Christine Bear, together with the group of Régis Pomès and collaborators at The Hospital for Sick Children and Proteostasis Therapeutics, used in silico, in vitro and ex vivo techniques to comprehensively understand the consequences of a rare Cystic Fibrosis (CF) disease-causing mutation in the CFTR gene: c.3700 A>G (ΔI1234_R1239), and subsequently develop a novel mechanism-based therapeutic strategy.

Steven Molinski, first author of the study and recent […]

Dr. Christine Bear

Christine Bear interviewed for the 25th anniversary of the CFTR gene discovery

1 October 2014|

In September, the Hospital for Sick Children celebrated the 25th anniversary of the discovery of the gene that causes Cystic Fibrosis: CFTR. To explain to the public the importance of the discovery, Christine Bear, Senior Scientist and Co-director of the Sick Kids Cystic Fibrosis Centre, was interviewed by several media outlets including CTV News, CBC, Global, and Cystic Fibrosis News Today.