Characterization of a new heme piracy pathway in Acinetobacter baumannii
The latest study from the Moraes lab characterized a novel heme uptake pathway in A. baumannii, which is listed by the WHO and CDC as one of the top priority pathogens for research and development of new therapeutics. In response to being in iron restricted environments such as a human host during infection, A. baumannii produces a heme binding protein (HphA) secreted by an outer membrane protein called Slam. This […]