|Address||160 College Street, room 1008
Toronto, ON M5S3E1
Dr. Attisano completed her PhD at the University of Toronto and conducted post-doctoral research at Memorial Sloan-Kettering Cancer Center in NYC, NY. She currently holds a Canada Research Chair in Signalling Networks in Cancer.
In the News
Research opportunities for undergraduate or graduate students and post-doctoral fellows with background and interests in molecular biology/biochemistry, mouse models, and/or high-throughput screening are available.
Learn more: Attisano Lab
Morphogen signalling pathways and the regulation of complex biological responses
My laboratory focuses on understanding how intracellular signalling cascades receive and then transmit extracellular signals and thereby modulate complex biological responses. Current areas of particular interest are the TGFbeta, Wnt and Hippo signalling pathways, whose disruption is associated with numerous human cancers. My lab also studies pathways that regulate neuronal morphology, including the formation of axons and dendrites in primary neurons. We use mammalian cell model systems and biochemical and cell biological methods, and mouse model systems to examine how pathway disruption alters cellular and developmental processes. In addition, we use high-throughput robotics-based methods to examine the dynamics of protein-protein interactions, and to screen for alterations in signalling output using siRNA and small-molecule chemical libraries.
BCH2132H Modelling Human Diseases from Cells to Organoids
BCH2024H Modelling human diseases from cells to organoids
BCH374Y1 Research Project in Biochemistry
BCH473Y Advanced Research Project in Biochemistry
BCH426H (BCH1426H) Regulation of Signalling Pathways
View all publications on PubMed