The Biochemistry of Translational Medicine
BCH2104H
This course will focus on reviewing scientific articles that use biochemistry and/or cell biology to help better understand human diseases. Emphasis will be on published scholarly work that provides examples of translational medicine or “bench-to-bedside” approach, which aims to expedite the discovery of new diagnostics and treatments.
– The first session will be an intro by both of us (~1h) followed by a discussion led by us about a paper (~1h).
– The intro will include some tips on how to present an article, etc.
– The other sessions will be 2 x 1 h sessions where one student presents a recent paper that provides an exciting example of an application of biochemistry to translational medicine (a second student will present another article during the second hour).
– Each student will be free to choose an article themselves or use one from the bank of articles provided by us (typically a very recent article published in of-of the top journals, such as Cell, Science, Nature, Nat Med, Nat Genetics, JCI, Sci Translat Med, etc.).
– Each student will also have to provide a short write-up (max 250 words) about the article presented that would be an abstract that could be read by a layperson (i.e., grade 7-8 education) + a relevant title. This is an important exercise because it is required for most grants that anyone submits.
– The format delineated above may need to be slightly amended depending on the number of students who end up enrolling for the class and do not withdraw.
Non-Biochemistry Students: This courses will be available to all non-Biochemsitry students to request through ACORN as follows:
Fall 2022 modules: September 1, 2022 – September 26, 2022(last day to add Fall courses)
**Important note for non-Biochemistry students – if you have one unpaired BCH2024 course, then you must contact carrie.harber@utoronto.ca to sign up for the second 1/4 module as per the deadlines listed above. Do not enroll through ACORN as your grades must be recorded under BCH 2024H Y – Focused Topic in Biochemistry.
Course Next Offered
Fall 2022 (Oct - Dec)
Course Time and Location
Start Date: Oct 25
End Date: Dec 13
Time: 2-4 pm
Day(s) of the Week: Tuesday
Note: We will likely only need 6 or 7 out of the 8 Tuesdays included in this time frame.
Course Location:
Building: Virtual or SickKids Research Institute (PGCRL; 686 Bay street)
Room: TBC
Enrollment Limit
Yes — 10
Method of Student Evaluation
Marks will be derived from:
- journal club presentation (70%)
- participation in other students’ presentations (20%)
- lay abstract (10%)
Coordinator
Mathieu Lemaire
Cell Biology Department
Peter Gilgan Centre For Research and Learning
SickKids Research Institute
686 Bay Street, room 19.9704
416-813-7654 ext. 309419
mathieu.lemaire@sickkids.ca
Aleixo Muise
PGCRL Tower
19.9400, J-Me
72 Elm Street
416-813-7735 or 416-813-5216
aleixo.muise@sickkids.ca