Islet Biology and Diabetes I: From Gene to Cell to Organ to Disease
BCH 2139
This 1/4 FCE graduate-level course will focus on a wide range of topics focused on the pancreatic islet. Each lecture will cover fundamental concepts in biochemistry with an emphasis on islet biology. These will include the impact of genetic variation on islet cells, the development of islet cell subpopulations, transcriptional networks and cell identity, biotechnological approaches, as well as communication between islet cells and the local environment, including components of the immune system, and how these interact to affect islet loss and dysfunction. A more integrated understanding of these processes will be facilitated in a discussion of islet-hormone regulated metabolic pathways and integrative physiology.
**THIS COURSE WILL BE ONLINE ONLY**
Please see below for Sign up procedure:
Students must take both BCH 2139H and BCH 2140H. Enrollment in only one of the courses is not permitted.
Link to Request BCH2139H & BCH 2140H starting in January, 2025:
Request Form for Islet Biology 2139+2140
Deadline to submit a request is October 25, 2024.
Given the current interest in this course, auditing will not be permitted this time.
University of Toronto Students: If approved for the course, you can request BCH 2139H on ACORN.
** Note if you were previously enrolled in BCH 2024H Y – Focused Topics in Biochemistry, and have not yet completed two modules, then you will need to contact the Biochemistry Department to sign up for BCH 2139H. You should NOT request this through ACORN.
Instead, you will remain enrolled in BCH 2024H and this module will be used towards completion of BCH 2024H. Your grade in BCH 2024H Y will be the average of your final grade for this course and the final grade of your last completed module under BCH 2024H Y.
Non-University of Toronto Students from Ontario and Canada: If approved for the course, you will need to complete one of the following:
- Students from Ontario Universities except (McGill University, Université de Montréal, and University of British Columbia) will need to complete an Ontario Visiting Graduate Student Agreement (OVGS) from their home University
- Students outside of Ontario and within Canada only will need to complete a Canadian University Graduate Transfer Agreement (CUGTA) from their home University
- Students from McGill University, Université de Montréal, and University of British Columbia will need to complete a Graduate Exchange Agreement (GEA) from their home University
**All paperwork must be submitted to the University of Toronto no later than Friday November 15, 2024 to ensure sufficient processing time.
**THIS COURSE WILL BE ONLINE ONLY**
Add date – Deadline to submit request (5:00 PM EST) – Will be announced in Fall, 2024
Drop date – Students have until the day before the first class to drop the course. Students can only drop the course after the first class with the permission of the instructor.
Course syllabus subject to change
Course Next Offered
January 2025
Course Time and Location
Time: Wednesday 1-3 pm EST
Start Date: January 8th, 2025
End Date: March 13th, 2024
Jan 8 Lecture 1
Jan 15 Lecture 2
Jan 22 Lecture 3
Jan 29 Lecture 4
Feb 5 Lecture 5
Feb 19 Lecture 6
Feb 26 Lecture 7
Mar 5 Lecture 8
Mar 12 Lecture 9
Enrollment Limit
Yes — 15
5 spots are reserved for Biochemistry grad students
Method of Student Evaluation
Participation 20%
News and Views Article – 40%
Lay News and Views Article - 40%
Coordinator
Robert Screaton
Sunnybrook Research Institute
2075 Bayview Avenue, Room M7 617
416-480-6100 X 5743
robert.screaton@sri.utoronto.ca