The Biochemistry of Translational Medicine

BCH 2024H

This course will focus on reviewing scientific articles that use biochemistry and/or cell biology to help better understand human diseases. Emphasis will be on scholarly work that provides examples of translational medicine or “bench-to-bedside” approach, which aims to expedite the discovery of new diagnostics and treatments.

 

Course Next Offered

Fall 2019 (Nov - Dec)

Course Time and Location

Start date: October 31
End date: December 20

Day(s) of the week: Thursday afternoon.
Time: 2:00 - 4:00 pm

Location: PGCRL (see below):

Oct 31, 2019 2:00 PM Presentations Intro lecture (1h) 18th Floor Rm. 18-189701

Nov 07, 2019 2:00 PM Presentations No lecture this week!

Nov 14, 2019 2:00 PM Presentations Articles #1 and #2 (1h each) 6th Floor Rm. 6-69701

Nov 21, 2019 2:00 PM Presentations Articles #3 and #4 (1h each) 18th Floor Rm. 18-189701

Dec 06, 2019 Assignment

Nov 28, 2019 2:00 PM Presentations Articles #5 and #6 (1h each) 18th Floor Rm. 18-189701

Dec 05, 2019 2:00 PM Presentations No lecture this week!

Dec 12, 2019 2:00 PM Presentations Articles #7 and #8 (1h each) 18th Floor Rm. 18-189701

Dec 19, 2019 2:00 PM Presentations Articles #9 and #10 (1h each) 18th Floor Rm. 18-189701

Dec 20, 2019 Assignment

Enrollment Limit

Yes — 10

Method of Student Evaluation

Marks will be derived from:
journal club presentation (70%)
participation in other students’ presentations (20%)
lay abstract (10%)

Here are a few extra details:
- We anticipate to have at least 5-6 students and no more than 10.
- The first session will be an intro by both of us (~1h) followed by a discussion led by us about a paper (~1h).
- The intro will include some tips on how to present an article, etc.
- The other sessions will 2 x 1 h sessions where one student present a recent paper that provides an exciting example of an application of biochemistry to translational medicine (a second student will present another article during the second hour).
- Each student will be free to choose an article themselves or use one from the bank of articles provided by us (typically a very recent article published in of-of the top journals, such as Cell, Science, Nature, Nat Med, Nat Genetics, JCI, Sci Translat Med, etc.).
- Each student will also have to provide a short write-up (max 250 words) about the article presented that would be an abstract that could be read by a layperson (i.e., grade 7-8 education) + a relevant title. This is an important exercise because it is required for most grants that anyone submits.
- The format delineated above may need to be slightly amended depending on the number of students who end up enrolling for the class (and do not withdraw)

Coordinator

Mathieu Lemaire

Mathieu Lemaire

Cell Biology Department
Peter Gilgan Centre For Research and Learning
SickKids Research Institute
686 Bay Street, room 19.9704

416-813-7654 ext. 309419
mathieu.lemaire@sickkids.ca

Aleixo Muise

Aleixo Muise

PGCRL Tower
19.9400, J-Me
72 Elm Street
416-813-7735 or 416-813-5216
aleixo.muise@sickkids.ca

Last Updated 15 November 2019