The GPD course, condensed into two full days and directed by Dr. Nana Lee, will highlight strategic communications and self-marketing to land dream careers. Workshop will be tailored to participants’ interests. Previous GPD trainees have succeeded in obtaining careers as listed here. Dates are June 3 and June 17 from 10:30 – 6 (MSB 5231) with a site visit to Janssen Pharmaceuticals Friday July 8, 10-12. PDF registration […]
Prion disease occurs when the normal cellular prion protein (PrPC) is misfolded by a pathogenic form of the protein termed PrP scrapie (PrPSc). One approach to treat prion diseases is to reduce or eliminate PrPC since mice lacking this protein show few ill effects. The human-approved immunosuppressive drug FK506 has been shown to extend survival in prion infected mice but the mechanism has been controversial. In a paper published in the […]
The 2015 Biochemistry Holiday party was, as in previous years, quite a memorable and fun night. Held on a rainy November 27th evening at the Hotel Ocho, the atmosphere was warm, elegant and very welcoming. Students and faculty were dressed to impress, and it was certainly a nice change to see everyone without lab coats and outside of class. The early birds got to enjoy some cheese, crackers and mingling […]
From 1934-1939 Dr. Benjamin (Benny) Schachter worked in the Department of Biochemistry conducting research on female sex hormones, isolating and identifying conjugated oestrone sulphate (Premarin). To honour Benny Schachter’s memory, a donation was made to the Department by his family. The funds are being used to support an annual lectureship in his memory. The BGSU and graduate students select and host the speaker who is a graduate from our Department.
This […]
Ramanujan Hegde from the MRC Laboratory of Molecular Biology, Cambridge, UK gave a tour-de-force presentation in our George Connell Seminar Series that focused on the quality control surveillance of tail-anchored membrane proteins and their insertion into ER and mitochondrial membranes.
As reported in our last correspondence, the Biochemistry Department fielded a softball team aptly named The Mutants this year. Despite our winning name, we had an awful season. We lost our first 6 games, tied the next, and then lost the last game which gave us a record of 0-7-1. Despite the losses, […]
July 14th saw the Biochemistry Department gathering once again for an exciting day of golf. Held at the Flemingdon 9-hole Golf Course in Midtown Toronto the threat of rain didn’t deter our intrepid golfers. Eight teams composed of beginners and experienced players enjoyed a “best ball” format that ensured that all golfers were able to contribute to their team’s effort. And it was a squeaker with the Pathological Lab Mates […]
Slx4 is a nuclease scaffold protein that is mutated in Fanconi Anemia patients. In his study, published in the EMBO Journal, Attila and colleagues in Grant Brown’s lab defined the pathway that assembles Slx4 protein complexes onto chromatin when DNA replication is blocked by DNA damaging drugs. Surprisingly, Slx4 complexes promote checkpoint signaling to allow cells to resist and repair DNA damage. Attila’s study, funded by […]
The Mutant Roster
Top Row, Left to Right: Mostafa, Martin, Steve, Brandon, Tomas, Eric, Emad, Marko, Bonnie, Graeme
Bottom Row, Left to Right: Sian, Renee, Trevor, Glenna, Baby Jude, David, Kristina, Tara
The Biochem Softball Team is together again after a two-year hiatus! The Mutants had their first game on May 22nd against the Iguanas. Despite the best efforts of the Mutants, they lost the game by 1 point. The team’s weakest inning […]
Mammalian Target of Rapamycin Complex 1 (mTORC1) is a master regulator of energy metabolism, protein synthesis, cell and animal growth, and it is implicated in numerous diseases, including cancer. Influx of essential amino acids such as Leu into cells is mediated by the LAT1-4F2hc (SLC7A5-SLC3A2) transporter in exchange for Gln, and results in the recruitment of the mTORC1 complex to the lysosomal membrane. Intracellular Leu then enters the lysosome to […]
More than 200 attendees and 80 posters contributed to another highly successful Research Day. Held in the Medical Sciences Auditorium with posters in the Stone Lobby, we also enjoyed a BBQ lunch on the “patio” in between.
As always, the calibre of science was extremely high, featuring research talks from trainees and our newest faculty members, as well as excellent poster presentations. We also enjoyed our annual Theo Hofmann Lecture (this year by […]
The 2015 Sela Cheifetz award for outstanding research for a Biochemistry Graduate Student was awarded to April Pawluk from the Davidson Lab.
April presented her work on the identification and analysis of novel anti-CRISPR genes.