Wael Demian from the Rotin lab at Sickkids, recently published a Cell Reports paper showing that the ion transporter NKCC1, known to regulate cell volume, forms a complex with the leucine transporter LAT1 and the Gln transporter ASCT2, and regulates mTORC1 activation via LAT1 and growth factors signaling. Thus, the work of Demian, et al. provides a long-sought link between cell size and cell mass.
News & Events
- Biochemistry Newsletter – Spring 2024 17 April 2024
- Biochemistry Golf Day is back! 30 June 2023
- Biochemistry November 2022 Newsletter 4 November 2022
- 2022-23 Biochemistry Specialists 5 October 2022
- Connell Lecture on Oct. 19th, 2022 4 October 2022
- Biochemistry Departmental Retreat 2022 30 September 2022