News & Events

jaspersen

Dr. Sue Jaspersen “‘Pore-ing’ into the yeast nucleus”

28 September 2016|

As part of the Connell Lecture Seminar Series, Dr. Sue Jaspersen from the Stowers Institute for Medical Research gave a seminar on how the spindle pole body duplicates in budding yeast, and how membrane-bound proteins enter the inner nuclear envelope.

An image of book cover for Success After Graduate School.

Hot off the press!

22 September 2016|

Success After Graduate School” is NOW available.

Drs. Nana Lee and Reinhart Reithmeier are the co-authors of this guidebook for graduate professional development designed to help create the pathway to your dream career. Special thanks to Nikko Torres for his illustrations and book design work. Thank-you to all students and faculty who helped shape this creation!

scherer-palazzo

Dr. Stephen Scherer – “Molecular Imbalance in Autism and Related Disorders”

16 September 2016|

As part of the 25th Anniversary of the Connell Lecture Seminar Series, Dr. Stephen Scherer from SickKids gave a seminar on the newest findings in genomics as applied to the understanding of complex diseases such as autism.

An image of Julie Forman-Kay.

Julie Forman-Kay elected as a Fellow to the Royal Society of Canada

13 September 2016|

FORMAN-KAY, Julie – Molecular Structure & Function Program, The Hospital for Sick Children, University of Toronto
Julie Forman-Kay is the foremost Canadian expert in developing and applying tools to study the structure, interactions and functions of disordered proteins of significant biomedical relevance. Her work has led to scientific understanding of the importance of disordered proteins and links their dynamic properties and biological function, providing a foundation for novel therapeutic approaches. […]

Malnutrition.

Study indicates malnutrition in children may lead to severe impairments in liver function

7 September 2016|

A group led by Peter Kim and Robert Bandsma (Paediatrics) made a breakthrough published in Journal of Cell Biology and in the Journal of Hepatology in linking peroxisome function through the gene PEX2 and the cell’s response to starvation.

Malnourished children living in the same household who are given the same food to eat sometimes have stark differences in health, leading researchers to query why some severely malnourished […]

The Biochemistry Department enjoying the great outdoors at Geneva Park

2016 Biochemistry Retreat at Geneva Park

27 August 2016|

On August 25th and 26th, the Biochemistry Department held its first Retreat outside of Toronto at the Geneva Park Conference Centre near Orillia.

The turnout was terrific with 140 trainees, staff and Faculty gathering for two days to celebrate the science that we do and to enjoy each other’s company in a beautiful lakeside setting. The Retreat featured cutting-edge talks by trainees and Faculty members as well as an evening poster session […]

Twenty-three trainees, staff and faculty enjoyed a terrific day of golf at our 2016 Biochemustrry Golf Day

2016 Biochemistry Golf Day

9 August 2016|

August 9th dawned hot and steamy but that didn’t deter our hardy biochemists from heading out to Flemingdon Park 9-hole Golf Course in Midtown Toronto for our annual Golf Day. Each team had its share of beginners and ringers playing a “best ball” format that allowed everyone to contribute to their team. Despite the 32 degree heat and sticky humidity the competition was fierce with the Dead Ringers pulling out […]

An image of models for two conformations of the AAA+ chaperone VAT, built into cryo-EM density maps.

Protein unfolding machinery visualized

9 August 2016|

Using a combined cryo-EM and solution NMR approach the laboratories of John Rubinstein and Lewis Kay have determined the structure and equilibrium distribution of two unique conformers along the ATP hydrolysis cycle of the AAA+ unfoldase VAT. The paper published in PNAS (http://www.pnas.org/content/113/29/E4190.abstract) lends insight into how this class of molecular machines are able to convert the chemical energy of ATP hydrolysis into the mechanical force required […]

An image of Gordon Dixon.

Passing of Gordon Henry Dixon

9 August 2016|

We are saddened to learn of the passing of Gordon Dixon on July 24, 2016. Gordon, a very accomplished biochemist, was Associate Professor in our Department for the period 1960-63.  Gordon was most recently  Professor Emeritus of Medical Biochemistry at the University of Calgary. He served as Department Chair there for 1983-88.

“During his illustrious academic career, he was the recipient of numerous accolades and international recognition. He served as President of […]

An image of word cloud of keywords in Dr. Fairn's publications. Since 2005, he has authored 35 publications including 32 focused on lipids and/or membrane biology.

Dr. Greg Fairn wins the 2017 Walter A. Shaw Young Investigator Award!

9 August 2016|

Dr. Greg Fairn, St. Micahel’s Hospital and Assistant Professor in the Departments of Biochemistry and Surgery, has won the 2017 Walter A. Shaw Young Investigator Award in Lipid Research from the American Society for Biochemistry and Molecular Biology. Dr. Fairn is also the first Canadian to win this award.

The award recognizes outstanding research contributions in the area of lipids by young investigators who are an Assistant professor or […]

An image of an atomic model of a ubiquitinated and dimethylated histone core particle with bound 53BP1 built into a cryo-EM density map.

Seeing the first steps of DNA repair

2 August 2016|

The laboratories of John Rubinstein and Frank Sicheri (Biochemistry), and Dan Durocher (Molecular Genetics) have used electron cryomicroscopy (cryo-EM) to determine the structure of the DNA-damage recognizing protein 53BP1 bound to modified nucleosome core particles. The work, published in Nature (http://www.nature.com/nature/journal/vaop/ncurrent/full/nature18951.html), was led by postdoctoral fellow Marcus Wilson and research associate Samir Benlekbir and provides the first structural insight into how dimethylation and ubiquitination of nucleosomes in […]

The annual poster session of the Biochemistry Summer Student Research Program.

Undergraduate Summer Students Share their Research

22 July 2016|

Each summer, the competitive Biochemistry Summer Student Research Program provides outstanding students with the unique opportunity to engage in research throughout the department. On Thursday July 21, 2016 students were able to share their findings in an annual poster session, outlining the goals of their project and describing their results.