News & Events

Avoiding catastrophe: Yeast study reveals clues to maintaining genome size

11 June 2018|

By Jovana Drinjakovic

Study reveals an unexpected role for a well- known protein machinery in maintaining the correct DNA content with implications for cancer and other diseases

As cells divide, they must accurately split their DNA between the two daughter cells or risk having an uneven number of chromosomes which can lead to developmental disorders and cancer. A new Donnelly Centre study uncovers how a […]

New Tools for Biofilm Disruption

8 June 2018|

Microbial biofilms grow on biotic and abiotic surfaces. The matrix of the biofilm that the pathogen produces protects them from the host immune response and antibiotics.  This proposes a major challenge for the treatment of chronic infections. In an article published in Plos Pathogens, Dustin J. Little and Roland Pfoh (Howell lab) and co-authors demonstrate that the C-terminal domain of PgaB is a glycoside hydrolase that can hydrolyze […]

Dr. Julie Forman-Kay was interviewed on Nature News Feature

1 June 2018|

Julie Forman-Kay was among a group of researchers interviewed for the Nature News Feature published on March 14, 2018 entitled “What lava lamps and vinaigrette can teach us about cell biology”.

Like oil in water, the contents of cells can segregate into droplets. It’s called phase separation, and biologists are seeing it everywhere.

Lewis Kay: “We must continue to nurture the next generation of scientists”

23 May 2018|

In a recent article in the Globe and Mail, Dr. Lewis Kay discusses why it is important to continue to nurture the next generation of scientists.

Click here to read the full article.

An image of Dr. Joel Watts.

Joel Watts named Canada Research Chair in Protein Misfolding Disorders

7 May 2018|

Dr. Joel Watts was named a Tier 2 Canada Research Chair in Protein Misfolding Disorders for his research on understanding the relationship between groups of misfolded proteins and the progression of degenerative brain disease, such as Alzheimer’s and Parkinson’s diseases. Congratulations!

Biochemistry Specialists, Class of 2018

4 May 2018|

The Biochemistry Specialist Class of 2018 is 16 strong, with interests spanning diverse areas of study, including computational biology, systems biology, protein structure/function, and cell biology. Most are bound for graduate programs or professional schools in Canada and the US.  Congratulations, Class of 2018!

Enhancing Learning of Glucose Metabolism Through Animated and Interactive Media

4 May 2018|

Stavroula Andreopoulos, Derek Ng and Sian Patterson are awarded a 2018-2020 Elevation Grant from the Advancing Teaching and Learning in Arts & Science (ATLAS) initiatives fund. The proposal “Enhancing Learning of Glucose Metabolism Through Animated and Interactive Media” builds on the previously ATLAS funded pilot project “Visual and Interactive Media for Deeper Molecular Understanding of Enzyme Kinetics” and will help further develop a long-term mutually beneficial collaboration […]

Visual and Interactive Media for Biochemistry Education

4 May 2018|

Stavroula Andreopoulos and Derek Ng, a former member of biochemistry and now faculty in the Biomedical Communications program at UTM, presented their animation and interactive media project at the 2nd annual Arts & Science Teaching & Learning Projects Showcase. ATLAS (Advancing Teaching and Learning in Arts & Science) funding supported the development of […]

Undergraduate Awards News

4 May 2018|

BCH Specialist Maria Tereshchenko is this year’s GLSE Leadership Award recipient, an award recognizing both undergraduate student leadership and scholarship.  Maria is also featured in GLSE’s “Meet Undergraduate Students” series. Congratulations Maria on such a fine achievement!

 

Graduate Student Shawn Xiong is this year’s recipient of the TATP award, the second time in two years this prestigious award has been given to a TA involved in the undergraduate course […]

Lewis Kay wins the 2018 Gerhard Herzberg Canada Gold Medal!

2 May 2018|

Congratulations to Professor Lewis Kay for receiving the Gerhard Herzberg Gold Medal!

The full story is featured on UofT New, the Globe and Mail, and the CBC News.

Tipping Cell Signaling Pathways by Salts

11 April 2018|

Mechanistic Insights into Allosteric Regulation of the A2A Adenosine G protein-Coupled Receptor by Physiological Cations

Libin Ye1,2, Chris Neale3, Adnan Sljoka4, Brent Lyda5, Dmitry Pichugin1,2, Nobuyuki Tsuchimura4, Sacha T. Larda1,2, Régis Pomès2,6, Angel E. García3, Oliver P. Ernst2,7, Roger K. Sunahara5, R. Scott Prosser1,2,*

In a recent paper appearing in Nature Communications, Libin Ye (Prosser lab) and co-authors reveal the delicate balance between inactive states and activation intermediates by allosteric […]

Structure and Dynamics of Complexes of G Proteins and their Receptors

16 March 2018|

Ned Van Eps in the Ernst laboratory used DEER spectroscopy together with molecular modeling techniques to map the structure of a complex between a G-protein-coupled receptor (GPCR) and its G protein. A paper describing the methodology used for characterizing the binding interface of the rhodopsin–G protein complex has recently been published in PNAS. The authors discovered that the binding mode of G protein subtypes is distinct and key differences suggest […]