• NOD2

How bacterial invaders are sensed in the gut

25 October 2019|0 Comments

A new paper in the latest issue of Science describes how the bacterial-sensing proteins, NOD1/2, are recruited to the membranes of our gut cells for them to function to initiate a proper immune response. This involves the addition of a lipid, palmitoyl, to NOD1/2 by the palmitoyl-transferase ZDHHC5. Importantly variants of NOD2 that are associated […]

  • McQ and Lewis

Angus McQuibban awarded major funding for anti-neurodegenerative diseases drug discovery by AI

24 October 2019|0 Comments

Professor G. Angus McQuibban has just been awarded a $2.3-million Genome Canada grant.

The GAPP grant in a partnership with Cyclica and Rosetta Therapeutics (founded by Professors Angus McQuibban and Peter Lewis) will support drug discovery related to treating people with the long-term neurodegenerative diseases and will involve the use of artificial intelligence and machine learning. (full story […]

  • BandC

Red Cell Anion Exchanger Makes the Cover of Biophysical Journal

1 October 2019|0 Comments

Dario De Vecchis, a post-doctoral fellow in the laboratory of Dr. Antreas Kalli at Leeds, University, in a collaborative project with Reinhart Reithmeier used molecular dynamics simulations to build the first atomic scale model of the red cell anion exchanger in a complex lipid bilayer that mimics the native membrane. This work appeared in the […]

  • Pai

Pai lab visualize the inner workings of an enzyme

27 September 2019|0 Comments

Researchers from the Emil Pai Lab in collaboration with the Miller Lab (Depts. of Chemistry and Physics, University of Toronto) have pieced together a time-lapse movie revealing all the major steps during the catalytic cycle of an enzyme. This study, published in Science, is the most detailed depiction of such a process to date.

The communication […]

2019 Biochemistry Golf Day

5 July 2019|0 Comments

The forecasted rain stayed away for our 2019 Golf Day and golfers enjoyed a beautiful cloudy day with the sun making an appearance near the end of the round. Twenty-eight students, admins, Faculty and more than a few ringers headed out to the Flemingdon Park 9-hole Golf Course in mid-town Toronto. Each team had its […]