• SickKids Awards

SickKids-led researchers receive numerous grants from the Canada Foundation for Innovation

27 March 2021|0 Comments

Professors Julie Forman-Kay, Simon Sharpe, P. Lynne Howell and John Rubinstein were awarded new CFI funds to help bring new technology to SickKids.

Professors Julie Forman-Kay, and Simon Sharpe, received more than $1.6 million to build on the SickKids Structural and Biophysical Core (SBC) facility. These new funds will support critical enhancements to cutting-edge research, knowledge creation, […]

  • Liliana Attisano

Latest Platform Support Grant to the Attisano Lab to make advanced brain models

27 March 2021|0 Comments

Together with the Krembil Foundation, Brain Canada awarded a Platform Support Grant (PSG) to a team spearheaded by Professor Liliana Attisano. She will be receiving $1,425,000 to support the Applied Organoid Core (ApOC), an organoid production platform for modelling human brain development and disorders.

Functional cooperativity between the trigger factor chaperone and the ClpXP proteolytic complex

12 March 2021|0 Comments

Rizzolo K, Yu AYH, Ologbenla A, Kim SR, Zhu H, Ishimori K, Thibault G, Leung E, Zhang YW, Teng M, Haniszewski M, Miah N, Phanse S, Minic Z, Lee S, Caballero JD, Babu M, Tsai FTF, Saio T, Houry WA.

In this manuscript, Walid A. Houry’s group identified a potential co-translational degradation pathway in Gram negative […]

Dr. Nana Lee’s Global Outreach Continues

1 March 2021|0 Comments

Dr. Nana Lee continues to highlight her expertise on graduate professional development, mentorship, leadership, and equity, diversity and inclusion (EDI) at multiple speaking engagements in 2021. She brings her enthusiasm, charisma and innovative multiple, interactive tools through the virtual learning space to provide an inclusive, engaged audience.

Some of her speaking events the past two months […]

Development of antibiotics that dysregulate the Neisserial ClpP protease

1 March 2021|0 Comments

In this highly collaborative effort, the groups of Walid A. Houry, Emil F. Pai, Robert A. Batey, and Scott D. Gray-Owen describe the generation and characterization of novel antibiotics targeting the bacterial ClpP protease.

Evolving antimicrobial resistance has motivated the search for novel targets and alternative therapies. Caseinolytic protease (ClpP) has emerged as an enticing new […]