McQuibban Lab
Department of Biochemistry, University of Toronto
Publications
  1. Meglei G, McQuibban GA. (2009) The Dynamin-Related Protein Mgm1p Assembles into Oligomers and Hydrolyzes GTP To Function in Mitochondrial Membrane Fusion. Biochemistry. Feb 10. Pubmed
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  3. Yu L, Lopez A, Anaflous A, El Bali B, Hamal A, Ericson E, Heisler LE, McQuibban A, Giaever G, Nislow C, Boone C, Brown GW, Bellaoui M. (2008) Chemical-genetic profiling of imidazo[1,2-a]pyridines and -pyrimidines reveals target pathways conserved between yeast and human cells. PLoS Genet.  Nov;4(11):e1000284. Pubmed
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  5. Whitworth AJ, Lee JR, Ho VMW, Flick R, Chowdury R, McQuibban GA. (2008) Rhomboid-7 and HtrA2/Omi act in a common pathway with the Parkinson's disease factors Pink1 and Parkin. Dis. Model. Mech. Sep 19;1:168-174. Pubmed
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  7. Yang Y, Ouyang Y, Yang L, Beal MF, McQuibban A, Vogel H, Lu B. (2008) Pink1 regulates mitochondrial dynamics through interaction with the fission/fusion machinery. Proc Natl Acad Sci U S A. May 13;105(19):7070-5. Pubmed
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  9. McQuibban GA, Lee JR, Zheng L, Juusola M, Freeman M. (2006) Normal mitochondrial dynamics requires rhomboid-7 and affects Drosophila lifespan and neuronal function. Current Biology. May 23;16(10):982-9. Pubmed
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  11. McQuibban GA, Saurya S, Freeman M. (2003) Mitochondrial membrane remodelling regulated by a conserved rhomboid protease. Nature. May 29;423(6939):537-41 Pubmed
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  13. Pubmed all McQuibban papers
 
Molecular mechanisms of mitochondrial membrane dynamics and their relation to cell function
artwork courtesy of Ina Schuppe-Koistinenhttp://www.nick-lane.net/Scientific%20Art.htmshapeimage_2_link_0