Annelise Jorgensen Professor

Ph.D., Connecticut, 1974
Medical Sciences Building, Room 5318
416-978-4470
a.jorgensen@utoronto.ca

Structure, Function, and Biogenesis of Calcium-Storage-Release Sites of the Sarcoplasmic Reticulum in Adult and Developing Cardiac and Skeletal Muscle Cells



Research Synopsis
 
Structure, function, and biogenesis of calcium-storage-release sites of the sarcoplasmic reticulum in adult and developing cardiac and skeletal muscle cells.
 


Selected Publications

Yuan, S., Arnold, W., and Jorgensen, A.O. Biogenesis of transverse tubules and triads: Immunolocalization of the 1,4-dihydropyridine receptor, TS28 and the ryanodine receptor in rabbit skeletal muscle developing in situ. J. Cell Biol. 112:289-301 (1991).

Klietsch, R., Ervasti, J.M., Arnold, W., Campbell, K.P., and Jorgensen, A.O. Dystrophin- glycoprotein complex and laminin colocalize to the sarcolemma and transverse tubules of cardiac muscle. Circulation Research 72:349-360 (1993).

Jorgensen, A.O., Shen, A.C.-Y., Arnold, W., McPherson, P.S., and Campbell, K.P. The Ca2+-release channel/ryanodine receptor is localized in junctional and corbular sarcoplasmic reticulum in cardiac muscle. J. Cell Biol. 120:969-980 (1993).

Guo, W., Jorgensen, A.O., and Campbell, K.P. Characterization and ultrastructural localization of a novel 90 kDa phosphoprotein unique to skeletal muscle junctional sarcoplasmic reticulum. Accepted for publication in J. Biol. Chem., August 1994.

Franzini-Armstrong, C., and Jorgensen, A.O. Structure and development of E-C coupling units in skeletal muscle. Ann.Rev.Physiol. 56:509-34 (1994).

   

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