Regulation of Signalling Pathways

BCH426H (BCH1426H)

A variety of questions relating to signal transduction are investigated. How is calcium regulated in the cell and how does calcium regulate cell function? How are extracellular signals such as morphogens, growth factors or insulin, received and transmitted by intracellular proteins including kinases and phosphatases to control cellular proliferation and differentiation?

Topics to be covered

  • Liliana Attisano: General signal transduction, TGFβ signalling and pathway cross-talk
  • Amira Klip: Pathways that regulate glucose transporters and their metabolic implications
  • Khosrow Adeli: Signaling mechanisms regulating lipid metabolism
  • Stephane Angers: Wnt signalling pathway
  • Frank Sicheri: Kinase structure and function
  • Daniela Rotin: Phosphatases
  • Oliver Ernst: G-protein coupled receptors and visual signal transduction
  • Sergio Grinstein: Calcium signalling pathways

Course Next Offered

January 2016

Course Time and Location

Room 4171, Medical Sciences Building
11:00 - 12:00, Tuesdays and Thursdays

Prerequisites

BCH210H1 / BCH242Y1;
BCH311H1 / MGY311Y1 / PSL350H1

Distribution Requirement Status: This is a Science course
Breadth Requirement: Living Things and Their Environment (4)

Enrollment Limit

Yes — 80

Method of Student Evaluation

Two Midterm tests (50-60%*) and a final exam (40-50%*). *varies from year to year

Coordinator

Liliana Attisano

Liliana Attisano

160 College Street, room 1008
416-946-3129
liliana.attisano@utoronto.ca

Instructors

Last Updated 11 August 2015