Membrane Proteins: Structure and Function

BCH422H

This course will discuss the structure and function of membrane proteins with an emphasis on relevant methodologies. Selected transporters, channels and pumps will be used as examples to illustrate the current state of the art of membrane protein biochemistry.  Molecular aspects of disease processes linked to membrane proteins will be discussed, with an emphasis on how 3D structural information provides a basis for understanding function.

Membrane Protein Biogenesis - protein folding and insertion into the membrane will be discussed

Course Next Offered

September 2017

Course Time and Location

Timetable
Fall Term (Sept. - Dec.)
Tuesday, Thursday 11am - 12pm
rm 4279 Medical Sciences Building

Prerequisites

BCH210H1/242Y,
BCH311H1/MGY311Y/PSL350H1

Enrollment Limit

Yes — 80

Method of Student Evaluation

2 Assignments (total 25%),
Quizzes (5%)
1 Midterm (25%, 5%),
Final exam (40%)

Recommended Reading

We will be discussing current state of the art, and readings will be assigned from the current scientific literature.

Lecture notes will be provided in class and/or through portal.

Membrane Structural Biology 2nd Edition by Mary Luckey, Cambridge University Press (2014). (not required).

Additional Notes and Resources

BCH422 -2017 Syllabus
Includes lecture topics and schedule. The 2017 syllabus is also available on blackboard with all the course notes.

Coordinator

Trevor F. Moraes

Trevor F. Moraes

Rm 5366 Medical Sciences Building
1 King's College Circle
416-946-3048
trevor.moraes@utoronto.ca

Instructors

Last Updated 7 September 2017