Proteins: from Structure to Proteomics


Proteins are the main functional units of the cell. In this course, a detailed overview of protein structure, stability, folding, protein-ligand interactions, and enzyme catalysis will be given with strong emphasis on discussing the basic principles in the field. Biophysical methods as well as theoretical approaches to studying protein stability and folding will be presented. Finally, proteomic approaches to map protein-protein interactions will be discussed.


Important Dates

Exam 1 – January 25, 2016

Exam 2 – February 10, 2016

Exam 3 – March 4, 2016

Exam 4 – March 21, 2016

Exam 5 – April 8, 2016


Course Next Offered

January 2016

Course Time and Location

The course will be held every Monday, Wednesday, and Friday from 1:00 pm – 2:00 pm in room 4171 MSB. There will be 25 lectures and 5 discussion/question periods. Prior to attending the discussion/question period, students will be required to read a research paper. The paper will be presented at the session. Students will be asked to submit the assignments+discussion questions at the beginning of the discussion/question period. Final grade is the sum of grades of 5 assignments and 5 exams. The exams will include questions from the lectures, assignments, and discussion sessions. The exams will be held in MSB2172 and MSB4279. There will be no midterm or final for the course.

Enrollment Limit

Yes — 80

Method of Student Evaluation

• Assignments (on course material): 2 points each
• Discussion questions (on article): 2 points each
• Exams as follows:
S. Sharpe: Exam 1, 16 points, 1 hour
W. A. Houry: Exam 3, 16 points, 1 hour
A. Chakrabartty: Exam 2, 16 points, 1 hour
H. S. Chan: Exam 4, 16 points, 1 hour
J. Watts: Exam 5, 16 points, 1 hour


Walid A. Houry

Walid A. Houry

1 King's College Circle
Medical Sciences Building, Room 5308


Last Updated 27 August 2015