Press for department or members

Doctors’ Notes: Changing the way we fight bacteria

24 October 2016|

Featured in this week’s Doctors’ Notes column in Toronto Star, Prof. Justin Nodwell re-examines antimicrobial resistance and discusses what our researchers are doing to fight bacteria.

Read the full article here.

An image of book cover for Success After Graduate School.

Hot off the press!

22 September 2016|

Success After Graduate School” is NOW available.

Drs. Nana Lee and Reinhart Reithmeier are the co-authors of this guidebook for graduate professional development designed to help create the pathway to your dream career. Special thanks to Nikko Torres for his illustrations and book design work. Thank-you to all students and faculty who helped shape this creation!

An image of networking.

Strategic Networking for Graduate Students

19 April 2016|

Dr. Nana Lee’s article on networking was just published yesterday in University Affairs.

For those who have taken her course, hope this refreshes your notes. For future students, enjoy the strategies in advance.

http://www.universityaffairs.ca/career-advice/career-advice-article/essential-networking-tips-for-graduate-students/

A picture of Vincent Nadeau.

BCH Alum Vincent Nadeau and GPD featured in U of T Magazine

5 April 2016|

The Spring issue of U of T Magazine features our own GPD course and alum Vincent Nadeau. Masha Cemma, also featured in the article, is a 2012 graduate of Dr. Nana Lee’s GPD class.

http://magazine.utoronto.ca/feature/life-after-grad-school-phd-degree-careers-cynthia-macdonald/

An image of Slam protein.

Moraes lab identify a novel protein (Slam) required for the proper display of virulence factors in bacteria

23 March 2016|

In a paper published online on Feb 29, 2016 in Nature Microbiology, the Moraes lab investigated the transport of surface lipoproteins (SLPs) in Neisseria and discovered a key component of the transport process called SLAM.

Bacterial pathogens that cause gonorrhea and meningitis have developed a number of virulence factors to survive inside our body. One of […]

Williams lab unravels the mechanistic basis of a treatment for prion diseases

3 March 2016|

Prion disease occurs when the normal cellular prion protein (PrPC) is misfolded by a pathogenic form of the protein termed PrP scrapie (PrPSc). One approach to treat prion diseases is to reduce or eliminate PrPC since mice lacking this protein show few ill effects. The human-approved immunosuppressive drug FK506 has been shown to extend survival in prion infected mice but the mechanism has been controversial. In a paper published in the […]

PLVAP Diagram

Aleixo Muise and Sick Kids researchers find defect in blood vessels the cause of new intestinal disease

6 August 2015|

In a study published in Cellular and Molecular Gastroenterology and Hepatology, Aleixo Muise, Clinician-Scientist and Co-Director of the IBD Centre, and a team of Sick Kids researchers reveal that a genetic defect causes a mutation of the PLVAP gene. The mutation leads to the loss of the protein filter in blood vessels in the bowel. Further research into this new disease may lead to new treatments and a […]

News & Views "Structural biology: Arresting developments in receptor signalling” by Jeffrey Benovic.

Ernst lab contributes DEER spectroscopy to Nature paper on rhodopsin-arrestin complex structure

6 August 2015|

The GPCR-arrestin complex crystal structure was solved using data collected at the Stanford LCLS X-ray free electron laser. Ned van Eps and Lydia Caro from the Ernst lab used pulsed electron paramagnetic resonance spectroscopy to validate the rhodopsin–arrestin complex assembly. The study published online 22 July 2015 in Nature has been downloaded more than 22,000 times in the first week after publication.

New CIFR Research Programs

New CIFAR research program co-directed by Oliver P. Ernst and R.J. Dwayne Miller

7 July 2015|

A new CIFAR Research Program co-directed by Oliver P. Ernst and R.J. Dwayne Miller advertised in The Globe and Mail on June 24, 2015.

The Canadian Institute for Advanced Research launched four new research programs. Two Biochemistry faculty, Lewis E. Kay and Oliver P. Ernst, as well as R.J. Dwayne Miller from the Departments of Chemistry and Physics are members of the program […]

Dr. Warren L. Lee portrait

Warren Lee interviewed by CTV on flu treatment findings

12 June 2015|

Dr. Warren Lee, critical care physician and cell biologist with St. Michael’s Hospital, teamed up with drug researchers at Sunnybrook Hospital to test Vasculotide, a new drug treatment that prevents lung blood vessels from leaking when attacked by the flu virus. Previous flu drugs attempt to defeat the virus while Vasculotide successfully treats the host.

The research findings are published in Scientific Reports and announced in […]

Larry Moran Quoted in the New York Times Magazine

21 March 2015|

In a followup to an article on Junk DNA that appeared in the New York Times Magazine on March 8th, the paper surveyed the reaction amongst online commentators. In the article Larry Moran was quoted:

the general public has been snowed by the Encode publicity campaign and by naïve journalists who have enthusiastically reported that junk DNA is dead.

Yuqing Wang

Grad Student Yuqing Wang featured in Faculty of Medicine News article

5 March 2015|

 

Yuqing Wang was featured in the article She Does It Her Way (And It Works) for the Faculty of Medicine News webpage. Yuqing, a PhD grad student in the Peter Kim and Angus McQuibban Labs, discussed her challenges and numerous triumphs in her studies and life in Canada.