Jolyn Duan

About Jolyn Duan

This author has not yet filled in any details.
So far Jolyn Duan has created 93 blog entries.

Dr. Stavroula Andreopoulos wins 2017 Sustained Excellence and Innovation in Life Sciences Education Award

Congratulations to Dr. Stavroula Andreopoulos on receiving the 2017 Sustained Excellence and Innovation in Life Sciences Education Award.

This award will be presented at the 15th Annual Education Achievement Celebration on May 15th.

21 March 2017|

Stagljar lab reveals new interactions among GPCRs

Using the modified membrane yeast two‐hybrid (MYTH) technology, researchers from the Stagljar lab mapped membrane protein interactions for clinically important G protein coupled receptors (GPCRs).

Read the full story on Faculty of Medicine website.

Read their paper on Molecular Systems Biology.

 

16 March 2017|

Dr. Sergio Grinstein wins the 2017 Canadian Science Publishing Senior Investigator Award!

Dr. Sergio Grinstein was selected by the Canadian Society for Molecular Biosciences as this year’s recipient of the  Canadian Science Publishing Senior Investigator Award. He will present his award talk at the upcoming meeting of the CSMB in Ottawa in May of this year.

1 March 2017|

Researchers revisit the role of conformational dynamics and the protein ensemble in catalysis

21 February 2017|

Houry lab identifies a novel regulator of respiratory chain complexes

Graphical abstract_120616

An interaction between the respiratory enzyme fumarate reductase (Frd, also known as Complex II) and an ATPase has been identified in E. coli by the Houry lab. The research shows that the RavA ATPase, belonging to a poorly characterized but ubiquitous MoxR family of AAA+ ATPases, associates with the Frd respiratory enzyme through an adaptor, which the group named ViaA. […]

13 February 2017|

Ernst Lab discover new way to crystallize membrane proteins

The laboratory of Dr. Oliver Ernst has used X-ray crystallography to determine the structure of a membrane protein that never left a lipid-bilayer environment (i.e., without the use of conventional detergents). The work, published in Structure and highlighted on the Journal’s cover, was led by postdoctoral fellow Dr. Jana Broecker. Polymer-bounded lipid nanodiscs were used to extract and purify membrane proteins with their surrounding lipids and allowed […]

7 February 2017|

Ensminger lab discovers a class of bacterial effectors with novel regulatory activities

Many bacterial pathogens modulate their hosts through complex arsenals of effector proteins that are injected into host cell during infection. Indeed, the concept that effectors target host proteins and processes to modulate their activities is central to the current molecular understanding of host-pathogen interactions. Legionella pneumophila, the causative agent of a deadly pneumonia known as Legionnaires’ disease, has over 300 effectors, which is the largest known arsenal amongst bacterial pathogens. […]

3 February 2017|

Lingwood Lab discover new approach to rescue endogenous misfolded proteins

Newly made proteins which do not quite achieve the correct 3D shape in the ER are moved to the cell cytoplasm via a specific membrane pore, and broken down. Many disease causing gene mutations e.g. in cystic fibrosis, also result in misfolding of the mutant protein, and its transport though this pore, for cytoplasmic degradation. This pore is hijacked by some bacterial toxins which need to access the cytoplasm to […]

1 February 2017|

The roles of protein dynamics and water networks in catalysis visualized

The dimeric enzyme fluoroacetate dehalogenase is one of only a handful of protein catalysts that can break the strongest bond in organic chemistry, the one between carbon and fluorine atoms, in the process transforming the highly toxic pesticide fluoroacetate into glycolate, a benign molecule.  The laboratories of Emil Pai and Scott Prosser, together with the group of Régis Pomès and collaborators in the US and Japan, have […]

1 February 2017|

Stagljar lab map interactions between receptor tyrosine kinases (RTKs) and protein tyrosine phosphatases (PTPs)

Featured on the front page of Molecular Cell, the research led by Dr. Igor Stagljar captured and mapped interactions between receptor tyrosine kinases (RTKs) and protein tyrosine phosphatases (PTPs) in human cells, leading to new and improved cancer therapies.

Read the full story on the Faculty of Medicine and The Varsity websites.

1 February 2017|

Davidson and Maxwell help discover off-switches for CRISPR

 

Featured on the cover of Cell, Biochemistry’s Dr. Alan Davidson and Dr. Karen Maxwell helped to discover how to turn off CRISPR. Read the full story.

31 January 2017|

Biochemistry GPD featured by NSF

Our GPD program has been highlighted as one of four North American STEM professional development programs by Council of Graduate Schools/National Science Foundation in their just published report. Check out page 27!

CGS/NSF report on STEM professional development

10 January 2017|