Dr. Charles Deber, Senior Scientist in the Program in Molecular Structure & Function, Research Institute, Hospital for Sick Children, and Professor in the Department of Biochemistry, University of Toronto, has received the 2017 Bruce Merrifield Award of the American Peptide Society. The Award was created in 1997 in honour of Dr. R. Bruce Merrifield, who won the Nobel Prize in Chemistry in 1984. The Award is presented every two years […]
Biochemistry faculty member Penney Gilbert was named a Tier II Canada Research Chair in Endogenous Repair for her work on understanding the mechanisms that control muscle stem cell fate during skeletal muscle homeostasis and regeneration.
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In work led by postdoctoral fellow Mohammad T. Mazhab-Jafari, the Rubinstein laboratory used electron cryomicroscopy (cryo-EM) to determine the atomic structure of the membrane-bound region of a eukaryotic V-ATPase. This study, which was published in Nature, gives the first high-resolution structure for the membrane region of any rotary ATPase, a family of enzymes that includes proton pumping V-ATPases and proton-driven ATP synthases. The structure reveals several surprising features of […]
The academic school year is off to a great start and the Department of Biochemistry is pleased to welcome our incoming class of Biochemistry Specialists. The Biochemistry Specialist program is open to a small group of high caliber students who wish to pursue a career in research. This year’s cohort, see here in with Dr. Sian Patterson, 2nd from the left, has begun their laboratory training in BCH242Y, […]
Natalie Bamford, a former University of Toronto Biochemistry Specialist and current PhD student in the Howell lab, was recently awarded a prestigious Vanier Canada Graduate Scholarship from the Natural Sciences and Engineering Research Council of Canada (NSERC) to continue her studies. Natalie’s research focuses on understanding the biosynthesis of the fungal biofilm exopolysaccharide galactosaminogalactan.
“This is a new exciting project as little is known of fungal exopolysaccharide biosynthesis. I […]
Nine PhD trainees and early PDFs attended Trillium Therapeutics on September 30, 2016 to meet with their President and CEO, Dr. Niclas Stiernholm and their research team. We learned all about their R & D, their innovative industry postdoctoral program, biotech culture and enjoyed some company chocolates. Thank-you to Trillium!
“Success After Graduate School” is NOW available.
Drs. Nana Lee and Reinhart Reithmeier are the co-authors of this guidebook for graduate professional development designed to help create the pathway to your dream career. Special thanks to Nikko Torres for his illustrations and book design work. Thank-you to all students and faculty who helped shape this creation!
FORMAN-KAY, Julie – Molecular Structure & Function Program, The Hospital for Sick Children, University of Toronto
Julie Forman-Kay is the foremost Canadian expert in developing and applying tools to study the structure, interactions and functions of disordered proteins of significant biomedical relevance. Her work has led to scientific understanding of the importance of disordered proteins and links their dynamic properties and biological function, providing a foundation for novel therapeutic approaches. […]
A group led by Peter Kim and Robert Bandsma (Paediatrics) made a breakthrough published in Journal of Cell Biology and in the Journal of Hepatology in linking peroxisome function through the gene PEX2 and the cell’s response to starvation.
Malnourished children living in the same household who are given the same food to eat sometimes have stark differences in health, leading researchers to query why some severely malnourished […]
Using a combined cryo-EM and solution NMR approach the laboratories of John Rubinstein and Lewis Kay have determined the structure and equilibrium distribution of two unique conformers along the ATP hydrolysis cycle of the AAA+ unfoldase VAT. The paper published in PNAS (http://www.pnas.org/content/113/29/E4190.abstract) lends insight into how this class of molecular machines are able to convert the chemical energy of ATP hydrolysis into the mechanical force required […]
We are saddened to learn of the passing of Gordon Dixon on July 24, 2016. Gordon, a very accomplished biochemist, was Associate Professor in our Department for the period 1960-63. Gordon was most recently Professor Emeritus of Medical Biochemistry at the University of Calgary. He served as Department Chair there for 1983-88.
“During his illustrious academic career, he was the recipient of numerous accolades and international recognition. He served as President of […]