Jolyn Duan

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So far Jolyn Duan has created 88 blog entries.

Bear Lab shows that a new Cystic Fibrosis treatment improves function from a rare CFTR mutation in patient tissue

The laboratory of Christine Bear, together with the group of Régis Pomès and collaborators at The Hospital for Sick Children and Proteostasis Therapeutics, used in silico, in vitro and ex vivo techniques to comprehensively understand the consequences of a rare Cystic Fibrosis (CF) disease-causing mutation in the CFTR gene: c.3700 A>G (ΔI1234_R1239), and subsequently develop a novel mechanism-based therapeutic strategy.

Steven Molinski, first author of the study and recent […]

14 July 2017|

Announcing our 4th Annual Postdoc and Senior PhD Professional Development Workshop

“Strategic Self-Marketing: Landing the Job”

Dates: Fridays, July 14 and July 28, 2017.

Time: 10 am – 4 pm

Location: Medical Sciences Building Room 5231

Previous attendees are now at biotech, pharma, international postdoc fellowships, start-ups, knowledge translation, communications.

Attendees are expected to work a few hours outside of class to prepare career action plans, resumes, cover letters and presentations. Agenda will cover highlights in Dr. Lee’s GPD class. http://biochemistry.utoronto.ca/courses/bch2024h-professional-development/

Please register by noon […]

26 June 2017|

Dr. Scott Prosser wins the 2017 Jeremy Knowles Award!

Dr. Scott Prosser has received the 2017 Jeremy Knowles Award of the Royal Society of Chemistry.

Read the full story: http://www.rsc.org/ScienceAndTechnology/Awards/JeremyKnowlesAward/2017-winner.asp

11 May 2017|

Howell lab deduces the mechanism of type IV pilus motors

Howell lab

The type IV pilus is a long and sturdy grappling hook that bacteria use to attach to a surface and then pull themselves closer to the surface. They are important for virulence in many pathogens, including those that cause cholera, gonorrhoea, food-borne diseases, and multi-drug resistant hospital acquired infections. The molecular mechanism of the motors involved in throwing out and pulling […]

5 May 2017|

New genetic disease discovered by Drs. Aleixo Muise and Walter Kahr

Two of Biochemistry’s professors, Drs. Aleixo Muise and Walter Kahr have discovered a brand new genetic disease through their research at the Hospital for Sick Children.

Their research article is published on Nature Communications.

Their story was also highlighted on the Hospital for Sick Children, CBC The National and CBC News Network, and the Globe and Mail websites:

http://www.sickkids.ca/AboutSickKids/Newsroom/Past-News/2017/SickKids-team-identifies-new-disease-solves-medical-mystery.html

http://www.cbc.ca/news/thenational/new-disease-discovered-1.4054061

[…]

7 April 2017|

Visual and Interactive Media for Deeper Molecular Understanding of Enzyme Kinetics

Dr. Stavroula Andreopoulos and Dr. Derek Ng were awarded a 2017-2019 Elevation Grant from the Advancing Teaching and Learning in Arts & Science (ATLAS) initiatives fund. The proposal “Visual and Interactive Media for Deeper Molecular Understanding of Enzyme Kinetics” represents the start of a long-term mutually beneficial collaboration between the Department of Biochemistry and UTM’s Biomedical Communications (BMC) program. MScBMC students will design and develop a […]

3 April 2017|

Dr. Lewis Kay named a 2017 Canada Gairdner International Award Laureate!

Congratulatory message from the Chair

On behalf of the entire Biochemistry Department I would like to congratulate our esteemed colleague Dr. Lewis Kay on winning the Gairdner International Award, Canada’s highest science prize. Kay’s work on the development and use of nuclear magnetic resonance (NMR) techniques for investigating molecular motion and short lived conformations in large multiprotein complexes, or ‘seeing the unseeable’ to use the vernacular, has pushed boundaries […]

30 March 2017|

Dr. Stavroula Andreopoulos wins 2017 Sustained Excellence and Innovation in Life Sciences Education Award

Congratulations to Dr. Stavroula Andreopoulos on receiving the 2017 Sustained Excellence and Innovation in Life Sciences Education Award.

This award will be presented at the 15th Annual Education Achievement Celebration on May 15th.

21 March 2017|

Stagljar lab reveals new interactions among GPCRs

Using the modified membrane yeast two‐hybrid (MYTH) technology, researchers from the Stagljar lab mapped membrane protein interactions for clinically important G protein coupled receptors (GPCRs).

Read the full story on Faculty of Medicine website.

Read their paper on Molecular Systems Biology.

 

16 March 2017|

Dr. Sergio Grinstein wins the 2017 Canadian Science Publishing Senior Investigator Award!

Dr. Sergio Grinstein was selected by the Canadian Society for Molecular Biosciences as this year’s recipient of the  Canadian Science Publishing Senior Investigator Award. He will present his award talk at the upcoming meeting of the CSMB in Ottawa in May of this year.

1 March 2017|

Researchers revisit the role of conformational dynamics and the protein ensemble in catalysis

21 February 2017|

Houry lab identifies a novel regulator of respiratory chain complexes

Graphical abstract_120616

An interaction between the respiratory enzyme fumarate reductase (Frd, also known as Complex II) and an ATPase has been identified in E. coli by the Houry lab. The research shows that the RavA ATPase, belonging to a poorly characterized but ubiquitous MoxR family of AAA+ ATPases, associates with the Frd respiratory enzyme through an adaptor, which the group named ViaA. […]

13 February 2017|