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Time-lapse imaging of Clover-YAP WT (first movie) and 5SA (second movie) in MDA-MB231 cells. Localization of Clover-YAP WT (wild type) and 5SA (mutant at all five LATS targeting sites) was monitored before and after…
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In a collaborative project started during a sabbatical leave at Oxford, Reinhart Reithmeier and Antreas Kalli (Leeds) used computer simulations to characterize the dynamics of the human red blood cell anion transport protein Band 3…
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Acyldepsipeptides (ADEPs) compounds have bactericidal properties via dysregulating the activity of the highly conserved tetradecameric bacterial ClpP protease. In a recent publication in Cell Chemical Biology, Keith S. Wong and co-authors from the Houry group…
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Source: Steve Bryson, PhD Malaria is one of the most inflicting infectious diseases worldwide. Each year, an estimated 200 million people contract malaria and approximately 440,000 people succumb to the infectious disease. Scientists in the…
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By Jovana Drinjakovic Study reveals an unexpected role for a well- known protein machinery in maintaining the correct DNA content with implications for cancer and other diseases As cells divide, they must accurately split their…
