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News

  • Protein unfolding machinery visualized

    Using a combined cryo-EM and solution NMR approach the laboratories of John Rubinstein and Lewis Kay have determined the structure and equilibrium distribution of two unique conformers along the ATP hydrolysis cycle of the AAA+…
  • Dr. Greg Fairn wins the 2017 Walter A. Shaw Young Investigator Award!

    Dr. Greg Fairn, St. Micahel’s Hospital and Assistant Professor in the Departments of Biochemistry and Surgery, has won the 2017 Walter A. Shaw Young Investigator Award in Lipid Research from the American Society for Biochemistry…
  • Seeing the first steps of DNA repair

    The laboratories of John Rubinstein and Frank Sicheri (Biochemistry), and Dan Durocher (Molecular Genetics) have used electron cryomicroscopy (cryo-EM) to determine the structure of the DNA-damage recognizing protein 53BP1 bound to modified nucleosome core particles.…
  • Undergraduate Summer Students Share their Research

    Each summer, the competitive Biochemistry Summer Student Research Program provides outstanding students with the unique opportunity to engage in research throughout the department. On Thursday July 21, 2016 students were able to share their findings…
  • Andrews’ lab identifies potential new drug combinations for chronic lymphocytic leukemia

    In a paper recently published in the journal Blood, Dr. David Andrews’ group used high-content screening to test 320 kinase inhibitors and identify ones that, when given in combination with venetoclax, can overcome resistance to…